Identification of small molecules that interrupt the life cycle of Aphanomyces
Posted on 27.09.2023 | Last Modified 27.09.2023
Lead Researcher (PI): John Stavrinides
Institution:
University of Regina
Total WGRF Funding:
$72,910
Co-Funders:
Saskatchewan Pulse Growers
Start Date:
2022
Project Length:
3 Years
Objectives:
Develop a stain-based bioassay to distinguish between viable and nonviable resting spores of Aphanomyces. Conduct a high-throughput screen of 50,000 small molecules to identify those that can induce zoospore emergence. Validate candidate compounds identified from the screen and assess their efficacy using plant assays.