Identification of small molecules that interrupt the life cycle of Aphanomyces

Posted on 27.09.2023 | Last Modified 27.09.2023
Lead Researcher (PI): John Stavrinides
Institution: University of Regina
Total WGRF Funding: $72,910
Co-Funders: Saskatchewan Pulse Growers
Start Date: 2022
Project Length: 3 Years

Develop a stain-based bioassay to distinguish between viable and nonviable resting spores of Aphanomyces. Conduct a high-throughput screen of 50,000 small molecules to identify those that can induce zoospore emergence. Validate candidate compounds identified from the screen and assess their efficacy using plant assays.